Pharmacy Practice MCQ

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Pharmacy Practice MCQ, in this article we will solve, Practice MCQ on the topic, Pathophysiology of Haematological Diseases. Read following article for your reference.

Pathophysiology of Haematological Diseases

Which of the following is a common cause of iron deficiency anemia?

  1. A) Excessive iron intake
  2. B) Chronic blood loss
  3. C) Vitamin B12 deficiency
  4. D) Hemolysis

 

What is the primary role of iron in the body?

  1. A) DNA synthesis
  2. B) Oxygen transport
  3. C) Blood clotting
  4. D) Immune response

 

Which laboratory finding is typically seen in iron deficiency anemia?

  1. A) Macrocytic red blood cells
  2. B) Elevated serum ferritin
  3. C) Microcytic hypochromic red blood cells
  4. D) Elevated mean corpuscular volume (MCV)

 

Which of the following symptoms is NOT commonly associated with iron deficiency anemia?

  1. A) Fatigue
  2. B) Pallor
  3. C) Jaundice
  4. D) Shortness of breath

 

Megaloblastic anemia is commonly caused by a deficiency in which of the following?

  1. A) Iron
  2. B) Vitamin B12
  3. C) Vitamin D
  4. D) Calcium

 

Which of the following is a characteristic finding in megaloblastic anemia?

  1. A) Microcytic red blood cells
  2. B) Normocytic red blood cells
  3. C) Macrocytic red blood cells
  4. D) Hypochromic red blood cells

 

Which neurological symptom is associated with vitamin B12 deficiency?

  1. A) Muscle cramps
  2. B) Numbness and tingling
  3. C) Joint pain
  4. D) Hair loss

 

Which test is used to diagnose pernicious anemia?

  1. A) Serum ferritin
  2. B) Schilling test
  3. C) Hemoglobin electrophoresis
  4. D) Bone marrow biopsy

 

Sickle cell anemia is caused by a mutation in which gene?

  1. A) HBB gene
  2. B) F8 gene
  3. C) G6PD gene
  4. D) HFE gene

 

What shape do red blood cells take in sickle cell anemia?

  1. A) Spherical
  2. B) Elliptical
  3. C) Sickle-shaped
  4. D) Teardrop-shaped

 

Which of the following is a common complication of sickle cell anemia?

  1. A) Iron overload
  2. B) Vaso-occlusive crises
  3. C) Hemarthrosis
  4. D) Splenomegaly

 

Which medication is commonly used to reduce the frequency of sickling episodes in sickle cell anemia?

  1. A) Hydroxyurea
  2. B) Erythropoietin
  3. C) Deferoxamine
  4. D) Folic acid

 

Thalassemia is characterized by a defect in the production of which component of hemoglobin?

  1. A) Heme
  2. B) Globin chains
  3. C) Iron
  4. D) Oxygen

 

Which type of thalassemia is caused by mutations in the beta globin genes?

  1. A) Alpha thalassemia
  2. B) Beta thalassemia
  3. C) Delta thalassemia
  4. D) Gamma thalassemia

 

What is a common treatment for patients with severe thalassemia?

  1. A) Iron supplementation
  2. B) Blood transfusions
  3. C) Vitamin B12 injections
  4. D) Bone marrow biopsy

 

Which complication is associated with frequent blood transfusions in thalassemia patients?

  1. A) Iron deficiency
  2. B) Iron overload
  3. C) Vitamin D deficiency
  4. D) Hypercalcemia

 

Hereditary spherocytosis is caused by a defect in which part of the red blood cell?

  1. A) Hemoglobin
  2. B) Cell membrane
  3. C) Nucleus
  4. D) Mitochondria

 

Which enzyme deficiency is associated with G6PD deficiency anemia?

  1. A) Glucose-6-phosphate dehydrogenase
  2. B) Pyruvate kinase
  3. C) Hexokinase
  4. D) Lactate dehydrogenase

 

Aplastic anemia is characterized by which of the following findings?

  1. A) Hypercellular bone marrow
  2. B) Pancytopenia
  3. C) Elevated reticulocyte count
  4. D) Increased red blood cell production

 

Anemia of chronic disease is often associated with which of the following conditions?

  1. A) Acute infections
  2. B) Chronic inflammatory diseases
  3. C) Vitamin B12 deficiency
  4. D) Hemolysis

 

Hemophilia A is caused by a deficiency in which clotting factor?

  1. A) Factor VIII
  2. B) Factor IX
  3. C) Factor XI
  4. D) Factor XIII

 

Which inheritance pattern is associated with hemophilia?

  1. A) Autosomal dominant
  2. B) Autosomal recessive
  3. C) X-linked recessive
  4. D) Mitochondrial

 

Which of the following is a common symptom of hemophilia?

  1. A) Hemarthrosis
  2. B) Thrombocytopenia
  3. C) Leukopenia
  4. D) Polycythemia

 

What is the primary treatment for hemophilia?

  1. A) Iron supplementation
  2. B) Clotting factor replacement therapy
  3. C) Bone marrow transplant
  4. D) Immunosuppressive therapy

 

Which of the following is a common diagnostic test for sickle cell anemia?

  1. A) Serum ferritin
  2. B) Hemoglobin electrophoresis
  3. C) Schilling test
  4. D) Bone marrow biopsy

 

Which vitamin deficiency is associated with megaloblastic anemia and neurological symptoms?

  1. A) Vitamin C
  2. B) Vitamin D
  3. C) Vitamin B12
  4. D) Vitamin K

 

Which of the following conditions is characterized by microcytic hypochromic anemia?

  1. A) Iron deficiency anemia
  2. B) Megaloblastic anemia
  3. C) Sickle cell anemia
  4. D) Aplastic anemia

 

Which of the following is a potential complication of untreated iron deficiency anemia?

  1. A) Hemarthrosis
  2. B) Heart failure
  3. C) Stroke
  4. D) Splenomegaly

 

Which genetic disorder is associated with the production of abnormal hemoglobin S?

  1. A) Thalassemia
  2. B) Sickle cell anemia
  3. C) Hemophilia
  4. D) Hereditary spherocytosis

 

Which treatment is commonly used to prevent iron overload in patients receiving frequent blood transfusions?

  1. A) Iron supplementation
  2. B) Iron chelation therapy
  3. C) Vitamin B12 injections
  4. D) Erythropoiesis-stimulating agents

 

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