Pharmacy Practice MCQ- Complexation

Pharmacy Practice MCQ, in this article we will solve, Practice MCQ under subject Physical Pharmaceutics. Read following article for your reference.

Complexation: Mechanism And Applications » PHARMACAREERS

What is complexation?
- A) Formation of a single molecule
- B) Interaction between two or more molecules to form a complex
- C) Breaking down of molecules
- D) None of the above
Which type of bond involves the sharing of electron pairs between atoms?
- A) Ionic Bonds
- B) Covalent Bonds
- C) Hydrogen Bonds
- D) Van der Waals Forces
What is a ligand in the context of complexation?
- A) The molecule that accepts electrons
- B) The molecule that donates electrons
- C) The molecule that breaks down
- D) None of the above
Which type of complex involves the coordination of metal ions with ligands?
- A) Organic Molecular Complexes
- B) Inclusion Complexes
- C) Metal Ion Complexes
- D) None of the above
What is the role of cyclodextrins in inclusion complexes?
- A) To break down drugs
- B) To encapsulate drugs within their cavity
- C) To donate electrons
- D) None of the above
Which type of bond is known as a dative bond?
- A) Covalent Bonds
- B) Coordinate Covalent Bonds
- C) Hydrogen Bonds
- D) Ionic Bonds
What type of interaction is involved in hydrogen bonds?
- A) Sharing of electron pairs
- B) Attraction between a hydrogen atom and an electronegative atom
- C) Transfer of electrons
- D) None of the above
Which of the following is an example of a metal ion complex?
- A) Caffeine with gentisic acid
- B) Iron with deferoxamine
- C) Cyclodextrins with drugs
- D) None of the above
What is the primary benefit of complexation in drug formulation?
- A) Decreasing drug stability
- B) Enhancing solubility, stability, and bioavailability
- C) Reducing drug efficacy
- D) None of the above
Which type of complexation involves non-covalent interactions?
- A) Covalent Complexes
- B) Non-Covalent Complexes
- C) Both A and B
- D) None of the above
What is the main application of complexation in pharmaceuticals?
- A) Enhancing drug solubility
- B) Reducing drug toxicity
- C) Improving drug stability
- D) All of the above
Which bond type is typically irreversible under physiological conditions?
- A) Hydrogen Bonds
- B) Covalent Bonds
- C) Van der Waals Forces
- D) Ionic Bonds
What is the role of the substrate in complexation?
- A) To donate electrons
- B) To accept electrons
- C) To break down the complex
- D) None of the above
Which of the following is a non-covalent interaction?
- A) Covalent Bonds
- B) Coordinate Covalent Bonds
- C) Hydrogen Bonds
- D) None of the above
What is the significance of coordinate covalent bonds in metal ion complexes?
- A) They involve the sharing of electron pairs
- B) They involve one atom donating both electrons for the bond
- C) They are weaker than hydrogen bonds
- D) None of the above
Which type of complexation can enhance the solubility of poorly soluble drugs?
- A) Covalent Complexes
- B) Inclusion Complexes
- C) Metal Ion Complexes
- D) None of the above
What is the primary interaction in van der Waals forces?
- A) Sharing of electron pairs
- B) Attraction between temporary dipoles
- C) Transfer of electrons
- D) None of the above
Which type of complexation is used to mask the bitter taste of drugs?
- A) Metal Ion Complexes
- B) Organic Molecular Complexes
- C) Inclusion Complexes
- D) None of the above
What is the role of analytical methods in studying complexation?
- A) To break down complexes
- B) To analyze the formation and stability of complexes
- C) To reduce drug efficacy
- D) None of the above
Which of the following is an example of an inclusion complex?
- A) Iron with deferoxamine
- B) Caffeine with gentisic acid
- C) Cyclodextrins with drugs
- D) None of the above
What type of bond is formed between a hydrogen atom and an electronegative atom?
- A) Covalent Bonds
- B) Coordinate Covalent Bonds
- C) Hydrogen Bonds
- D) Ionic Bonds
Which type of complexation involves the encapsulation of one molecule within another?
- A) Metal Ion Complexes
- B) Organic Molecular Complexes
- C) Inclusion Complexes
- D) None of the above
What is the primary benefit of using cyclodextrins in drug formulation?
- A) To break down drugs
- B) To enhance drug solubility and stability
- C) To reduce drug efficacy
- D) None of the above
Which type of bond is stronger than hydrogen bonds but weaker than covalent bonds?
- A) Ionic Bonds
- B) Coordinate Covalent Bonds
- C) Van der Waals Forces
- D) None of the above
What is the role of metal ions in metal ion complexes?
- A) To donate electrons
- B) To accept electrons
- C) To break down the complex
- D) None of the above
Which type of complexation can improve the bioavailability of drugs?
- A) Covalent Complexes
- B) Non-Covalent Complexes
- C) Both A and B
- D) None of the above
What is the primary interaction in ionic bonds?
- A) Sharing of electron pairs
- B) Attraction between oppositely charged ions
- C) Transfer of electrons
- D) None of the above
Which type of complexation is used in the treatment of iron overload conditions?
- A) Metal Ion Complexes
- B) Organic Molecular Complexes
- C) Inclusion Complexes
- D) None of the above
What is the significance of hydrogen bonds in complexation?
- A) They involve the sharing of electron pairs
- B) They involve the attraction between a hydrogen atom and an electronegative atom
- C) They are stronger than covalent bonds
- D) None of the above
Which type of complexation involves the interaction between organic molecules?
- A) Metal Ion Complexes
- B) Organic Molecular Complexes
- C) Inclusion Complexes
- D) None of the above

Leave a Comment Cancel reply