Pharmacy Practice MCQ

Pharmacy Practice MCQ, in this article we will solve, Practice MCQ under subject physical pharmaceutics II. Read following article for your reference.

Photolytic Degradation And Its Prevention » PHARMACAREERS

What does photolytic degradation refer to?
- A. Degradation of a drug due to exposure to heat
- B. Degradation of a drug due to exposure to light
- C. Degradation of a drug due to exposure to moisture
- D. Degradation of a drug due to exposure to air
Which type of light most commonly causes photolytic degradation in pharmaceuticals?
- A. Infrared light
- B. Ultraviolet light
- C. Visible light
- D. X-ray light
What is a primary consequence of photolytic degradation in pharmaceuticals?
- A. Loss of potency
- B. Change in color
- C. Change in odor
- D. All of the above
How can photolytic degradation affect a drug’s efficacy?
- A. By increasing its therapeutic effects
- B. By reducing its therapeutic effects
- C. By making it more stable
- D. By preventing side effects
Which class of compounds is particularly susceptible to photolytic degradation?
- A. Proteins
- B. Steroids
- C. Amino acids
- D. Antibiotics
Which packaging material can help prevent photolytic degradation?
- A. Transparent glass
- B. Amber glass
- C. Paper
- D. Plastic
What role do stabilizers play in preventing photolytic degradation?
- A. They enhance drug dissolution
- B. They absorb harmful wavelengths of light
- C. They increase the drug’s weight
- D. They change the drug’s flavor
Which excipient can be added to formulations to reduce photolytic degradation?
- A. Sorbitol
- B. Titanium dioxide
- C. Lactose
- D. Sucrose
How does the International Conference on Harmonisation (ICH) guideline Q1B relate to photolytic degradation?
- A. It provides guidelines for drug dissolution testing
- B. It provides guidelines for photostability testing
- C. It provides guidelines for bioavailability studies
- D. It provides guidelines for clinical trials
Why is photostability testing crucial in the pharmaceutical industry?
- A. To ensure drug efficacy under all storage conditions
- B. To assess the drug’s color and flavor stability
- C. To determine the manufacturing process
- D. To evaluate the drug’s marketability
Which factor does NOT affect the rate of photolytic degradation?
- A. Intensity of light
- B. Exposure duration
- C. Drug concentration
- D. Room temperature
What is the primary purpose of using amber glass bottles for pharmaceuticals?
- A. To reduce the drug’s weight
- B. To protect the drug from light
- C. To enhance the drug’s appearance
- D. To improve drug dissolution
What type of study is conducted to evaluate a drug’s sensitivity to light?
- A. Thermal stability study
- B. Photostability study
- C. Humidity stability study
- D. Chemical stability study
Which type of light is often used in photostability studies?
- A. Fluorescent light
- B. Halogen light
- C. Xenon light
- D. LED light
What is a common indication that a drug has undergone photolytic degradation?
- A. Weight increase
- B. Change in physical state
- C. Discoloration
- D. Increase in potency
Which mechanism can reduce the risk of photolytic degradation in drug formulations?
- A. Using opaque packaging
- B. Storing the drug in a refrigerator
- C. Increasing the drug’s concentration
- D. Reducing the drug’s molecular weight
What is the impact of light exposure on the stability of vitamins in pharmaceuticals?
- A. It enhances the stability of vitamins
- B. It reduces the stability of vitamins
- C. It has no effect on vitamin stability
- D. It increases the bioavailability of vitamins
What does the term “photostability” mean in the context of pharmaceuticals?
- A. The drug’s resistance to moisture
- B. The drug’s resistance to light-induced degradation
- C. The drug’s resistance to heat
- D. The drug’s resistance to microbial contamination
Which of the following is NOT a method to prevent photolytic degradation?
- A. Using UV-blocking agents
- B. Adding antioxidants
- C. Using light-resistant packaging
- D. Increasing drug dosage
Why are antioxidants added to drug formulations?
- A. To improve the drug’s taste
- B. To prevent oxidation and photolytic degradation
- C. To increase the drug’s solubility
- D. To enhance the drug’s color
Which light-blocking material is commonly used in drug packaging?
- A. Aluminum foil
- B. Polyethylene
- C. Cellulose
- D. Silicone
What is a common characteristic of drugs prone to photolytic degradation?
- A. They are highly soluble in water
- B. They have complex molecular structures
- C. They are sensitive to low temperatures
- D. They are biologics
What does the term “photoprotection” refer to in pharmaceuticals?
- A. Protection against microbial contamination
- B. Protection against light-induced degradation
- C. Protection against thermal degradation
- D. Protection against chemical reactions
How can photolytic degradation be detected in pharmaceuticals?
- A. By visual inspection
- B. By chemical analysis
- C. By stability testing
- D. All of the above
Why is it important to test for photolytic degradation during the drug development process?
- A. To ensure the drug’s stability and efficacy
- B. To reduce manufacturing costs
- C. To meet marketing requirements
- D. To determine the drug’s flavor profile
Which type of photostability testing is performed to simulate real-world conditions?
- A. Accelerated testing
- B. Routine testing
- C. Stress testing
- D. Long-term testing
What does the term “UV stabilizers” refer to?
- A. Chemicals that enhance the drug’s color
- B. Chemicals that prevent UV-induced degradation
- C. Chemicals that increase the drug’s weight
- D. Chemicals that improve the drug’s taste
Why are photostability studies required by regulatory authorities?
- A. To ensure the safety and efficacy of drugs
- B. To assess the packaging design
- C. To determine the cost of production
- D. To evaluate the drug’s taste
What effect does photolytic degradation have on the shelf life of a drug?
- A. It shortens the shelf life
- B. It extends the shelf life
- C. It has no impact on shelf life
- D. It makes the drug more effective
How can the risk of photolytic degradation be minimized during drug storage?
- A. By using transparent containers
- B. By storing in dark places
- C. By increasing room temperature
- D. By exposing to artificial light

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