Centrifugation: Principles, applications and instruments used for centrifugation

Centrifugation Centrifugation is a pivotal process in pharmaceutical engineering, playing a crucial role in the separation and purification of various components. This technique leverages the principles of centrifugal force to isolate particles based on their size, shape, density, and viscosity. The importance of centrifugation in the pharmaceutical industry cannot be overstated, as it is essential … Read more

Silverson emulsifiers: Principal construction working uses merits and demerits

Silverson emulsifiers: Principal construction working uses merits and demerits In the pharmaceutical industry, the precision and efficiency of mixing processes are crucial for ensuring the quality and consistency of products. One of the most effective devices for creating stable emulsions is the Silverson emulsifier. Known for its high-shear mixing capabilities, the Silverson emulsifier is widely … Read more

Propellers, Turbines and Paddles: Principle, construction, working, uses, merits and demerits

Propellers In the realm of pharmaceutical engineering, the efficiency and precision of mixing processes are paramount to ensuring the quality and consistency of pharmaceutical products. Among the various mixing devices, propellers stand out due to their simplicity and effectiveness in handling low-viscosity liquids and maintaining suspensions. This article explores the principle, construction, working, uses, merits, … Read more

Planetary mixers: Principle, construction, working, uses, merits and demerits

Planetary mixers: Principle, construction, working, uses, merits and demerits In the pharmaceutical industry, the precision and efficiency of mixing processes are crucial for ensuring the quality and consistency of products. One of the most versatile and effective mixing devices used in this field is the planetary mixer. Known for its unique mixing action, the planetary … Read more

Sigma blade mixer: Principle, construction, working, uses, merits and demerits

Sigma blade mixer: Principle, construction, working, uses, merits and demerits In the pharmaceutical industry, the mixing and kneading of high-viscosity materials are critical processes that ensure the uniformity and quality of final products. The Sigma blade blender, also known as a Sigma mixer or kneader, is a specialized piece of equipment designed to handle these … Read more

Ribbon blender: Principle, construction, working, uses, merits and demerits

Ribbon blender: Principle, construction, working, uses, merits and demerits In the pharmaceutical industry, the uniform mixing of powders and granules is essential for the consistency and efficacy of drug formulations. The ribbon blender, a versatile and widely used mixing device, plays a crucial role in achieving this uniformity. This article explores the principle, construction, working, … Read more

Twin shell blender: Principle, construction, working, uses, merits and demerits

Twin shell blender: Principle, construction, working, uses, merits and demerits In the pharmaceutical industry, achieving a homogeneous blend of powders and granules is crucial for the consistency and efficacy of drug formulations. The twin shell blender, also known as a V-blender, is a widely used piece of equipment designed to meet this need. This article … Read more

Double cone blender: Principle construction working uses merits and demerits

Double cone blender: Principle construction working uses merits and demerits In the realm of pharmaceutical engineering, the double cone blender stands out as a pivotal piece of equipment designed for the homogeneous mixing of dry powders and granules. This blending apparatus is indispensable in ensuring the uniform distribution of active pharmaceutical ingredients (APIs) and excipients, … Read more

Mechanism of solid mixing, liquid mixing and semisolid mixing

Mechanism of solid mixing, liquid mixing and semisolid mixing Mixing is a critical unit operation in pharmaceutical engineering, essential for ensuring the uniformity, stability, and efficacy of pharmaceutical products. The process involves combining different components to achieve a homogeneous mixture, which is crucial for the consistent quality of the final product. This article delves into … Read more

Objectives, applications and factors affecting mixing and difference between solid and liquid mixing

Objectives, applications and factors affecting mixing and difference between solid and liquid mixing Mixing is a fundamental process in pharmaceutical engineering, playing a crucial role in the production of various dosage forms. The primary objective of mixing is to achieve a homogeneous blend of different components, ensuring uniformity in the final product. This process is … Read more