Pharmacodynamics- Principles and Mechanism of Drug Action Pharmacodynamics, a core area of pharmacology, delves into the intricate interactions between drugs and the biological systems they affect. Unlike pharmacokinetics, which focuses on the absorption, distribution, metabolism, and excretion of drugs, pharmacodynamics explores the effects of drugs on the body and how these effects are achieved. This … Read more
Distribution of drugs Distribution in pharmacokinetics refers to the reversible movement of a medication from one part of the body to another. A medication needs to be dispersed into intracellular and interstitial fluids after it is directly administered or absorbed and goes into systemic circulation. Once a medication enters the bloodstream, it is dispersed to … Read more
Absorption of drugs Absorption is defined as the movement of drugs or medications from its site of administration into the bloodstream. The rate of absorption is just as significant as the portion of the administered dose that is absorbed. The medication must pass through biological membranes, unless it is administered intravenously. Absorption is governed by … Read more
Pharmacokinetics Pharmacokinetics is defined as the quantitative study of a drug’s entry, passage through, and exit from the body. The pharmacokinetic properties of the drug determine its concentration at the site of action, which in turn affects the intensity of response. The route of administration, dosage, latency of onset, time of peak action, duration of … Read more
Introduction Routes of drug administration plays an important role to obtain maximum benefit from the drug. Drug administered into the body goes through several metabolic changes which affect the bioavailability of drug. Bioavailability is the proportion of drug that is available at site of action. Therefore, route of administration is important for maximum bioavailability. An … Read more
Introduction The term pharmacology is derived from two Greek words pharmakon means drug and logos, means science. Pharmacology is the scientific study of the effects of drugs and chemicals on living organisms. It includes study of sources of drugs, their mechanism of action, toxicity, absorption, distribution, metabolism and excretion of drugs. Drugs and their uses … Read more