Pharmacy Practice MCQ, in this article we will solve, Practice MCQ under subject Microbiology. Read following article for your reference.
Evaluation Of Bactericidal & Bacteriostatic » PHARMACAREERS
1. What is the primary function of bactericidal agents?
a) Inhibit bacterial growth
b) Kill bacteria
c) Promote bacterial growth
d) Neutralize toxins
What is the primary function of bacteriostatic agents?
a) Inhibit bacterial growth
b) Kill bacteria
c) Promote bacterial growth
d) Neutralize toxins
Which test is commonly used to evaluate the bactericidal activity of a substance?
a) Kirby-Bauer disk diffusion test
b) Minimum inhibitory concentration (MIC) test
c) Time-kill assay
d) Polymerase chain reaction (PCR)
What is the Minimum Inhibitory Concentration (MIC)?
a) The highest concentration of a drug that kills bacteria
b) The lowest concentration of a drug that inhibits bacterial growth
c) The highest concentration of a drug that inhibits bacterial growth
d) The lowest concentration of a drug that kills bacteria
What is the Minimum Bactericidal Concentration (MBC)?
a) The highest concentration of a drug that kills bacteria
b) The lowest concentration of a drug that inhibits bacterial growth
c) The highest concentration of a drug that inhibits bacterial growth
d) The lowest concentration of a drug that kills bacteria
Which of the following methods can determine whether an agent is bactericidal or bacteriostatic?
a) Kirby-Bauer disk diffusion test
b) Minimum inhibitory concentration (MIC) test
c) Time-kill assay
d) Broth dilution test
What does a bactericidal agent do to bacterial cells?
a) Inhibits their growth
b) Kills them
c) Allows them to replicate
d) Neutralizes their toxins
What is a common characteristic of bacteriostatic agents?
a) They kill bacteria instantly
b) They inhibit bacterial growth
c) They promote bacterial growth
d) They neutralize bacterial toxins
In a time-kill assay, what is being measured?
a) The growth rate of bacteria
b) The time it takes for bacteria to die
c) The concentration of bacteria over time
d) The effectiveness of bacteriostatic agents
What result indicates a bactericidal effect in a time-kill assay?
a) No change in bacterial count
b) Reduction in bacterial count
c) Increase in bacterial count
d) Stabilization of bacterial count
Which agent is more likely to be used for sterilization purposes?
a) Bactericidal agent
b) Bacteriostatic agent
c) Both equally
d) Neither
Which agent is more likely to be used in a clinical setting to treat infections?
a) Bactericidal agent
b) Bacteriostatic agent
c) Both equally
d) Neither
What does the term ‘bactericidal’ specifically imply about the agent’s activity?
a) It stops bacteria from dividing
b) It kills bacteria
c) It promotes bacterial growth
d) It prevents bacterial adherence
What does the term ‘bacteriostatic’ specifically imply about the agent’s activity?
a) It kills bacteria
b) It inhibits bacterial growth
c) It promotes bacterial growth
d) It prevents bacterial adherence
Which test involves measuring the optical density of a bacterial culture to evaluate the effect of an antimicrobial agent?
a) Kirby-Bauer disk diffusion test
b) Broth dilution test
c) Time-kill assay
d) Spectrophotometry
Why is the MIC test important in evaluating antimicrobial agents?
a) It determines the lowest concentration needed to kill bacteria
b) It determines the lowest concentration needed to inhibit bacterial growth
c) It determines the time it takes for bacteria to die
d) It measures the optical density of a bacterial culture
What does a clear zone around an antibiotic disk in the Kirby-Bauer test indicate?
a) Bacterial growth
b) Bacterial inhibition
c) Bacterial resistance
d) Bacterial adherence
Which agent would be preferred in treating a life-threatening infection where the immune system is compromised?
a) Bactericidal agent
b) Bacteriostatic agent
c) Both equally
d) Neither
How can the effectiveness of a bactericidal agent be confirmed after treatment?
a) By measuring the growth rate of bacteria
b) By counting the number of surviving bacteria
c) By observing bacterial adherence
d) By assessing bacterial metabolic activity
Which test can be used to differentiate between bactericidal and bacteriostatic effects?
a) Kirby-Bauer disk diffusion test
b) Time-kill assay
c) MIC test
d) Spectrophotometry
What is the significance of the MBC in evaluating an antimicrobial agent?
a) It helps determine the lowest concentration needed to inhibit bacterial growth
b) It helps determine the lowest concentration needed to kill bacteria
c) It measures the time required to kill bacteria
d) It assesses bacterial metabolic activity
Which type of agent is more likely to be used in a situation where the patient has a strong immune response?
a) Bactericidal agent
b) Bacteriostatic agent
c) Both equally
d) Neither
What does a reduction in colony-forming units (CFUs) indicate in a time-kill assay?
a) Bacterial growth
b) Bacterial adherence
c) Bactericidal activity
d) Bacterial resistance
Which agent relies on the host’s immune system to eliminate the bacteria after inhibition of growth?
a) Bactericidal agent
b) Bacteriostatic agent
c) Both equally
d) Neither
What is the significance of a time-kill curve in evaluating antimicrobial agents?
a) It shows the time required to kill bacteria
b) It shows the concentration required to inhibit bacterial growth
c) It shows the rate of bacterial resistance
d) It shows the bacterial adherence rate
Which agent is more suitable for use in disinfectants and sterilization processes?
a) Bactericidal agent
b) Bacteriostatic agent
c) Both equally
d) Neither
How does the presence of biofilm affect the efficacy of bactericidal agents?
a) It enhances the efficacy
b) It has no effect
c) It reduces the efficacy
d) It neutralizes the agent
What is a potential disadvantage of using bacteriostatic agents?
a) They kill bacteria instantly
b) They require the host’s immune system to clear the infection
c) They promote bacterial growth
d) They neutralize bacterial toxins
Which agent is more likely to cause the release of endotoxins upon bacterial cell lysis?
a) Bactericidal agent
b) Bacteriostatic agent
c) Both equally
d) Neither
Which test would you use to measure the effectiveness of an antimicrobial agent over a 24-hour period?
a) Kirby-Bauer disk diffusion test
b) Time-kill assay
c) MIC test
d) Broth dilution test
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