Pharmacy Practice MCQ, in this article we will solve, Practice MCQ under subject Microbiology. Read following article for your reference.
What is the primary purpose of sterility testing in pharmaceutical products?
a) To determine the potency of the product
b) To confirm the absence of viable microorganisms
c) To check the pH levels
d) To assess the color of the product
Which of the following pharmacopeias provide guidelines for sterility testing?
a) IP (Indian Pharmacopoeia)
b) BP (British Pharmacopoeia)
c) USP (United States Pharmacopeia)
d) All of the above
What is a common method used for sterility testing of liquid products?
a) Filtration
b) Centrifugation
c) Sedimentation
d) Precipitation
Which medium is typically used for the sterility testing of anaerobic microorganisms?
a) Fluid Thioglycollate Medium
b) Soybean Casein Digest Medium
c) Sabouraud Dextrose Medium
d) MacConkey Agar
What is the recommended incubation temperature range for sterility testing according to USP?
a) 15-20°C
b) 20-25°C
c) 30-35°C
d) 35-37°C
How long are samples typically incubated during sterility testing?
a) 7 days
b) 10 days
c) 14 days
d) 21 days
Which method is commonly used for sterility testing of solid products?
a) Membrane filtration
b) Direct inoculation
c) Centrifugation
d) Ultrasonication
In sterility testing, what is the purpose of using a negative control?
a) To confirm the growth of microorganisms
b) To ensure no contamination has occurred
c) To verify the effectiveness of the product
d) To measure the potency of the product
Which pharmacopeia specifies the use of Soybean Casein Digest Medium for sterility testing?
a) IP
b) BP
c) USP
d) All of the above
What is the importance of using positive controls in sterility testing?
a) To confirm the absence of contamination
b) To verify the sterility of the medium
c) To ensure the test system can support the growth of microorganisms
d) To measure the chemical properties of the product
Which method is suitable for sterility testing of ophthalmic products?
a) Direct inoculation
b) Membrane filtration
c) Centrifugation
d) Sedimentation
What is the role of Fluid Thioglycollate Medium in sterility testing?
a) It supports the growth of aerobic microorganisms
b) It supports the growth of anaerobic microorganisms
c) It inhibits the growth of fungi
d) It acts as a preservative
Which of the following is a key consideration when selecting a sterility testing method for a product?
a) The volume of the product
b) The type of microorganisms expected
c) The physical state of the product (solid, liquid, etc.)
d) All of the above
Which sterility testing method involves passing the test sample through a filter membrane?
a) Direct inoculation
b) Membrane filtration
c) Centrifugation
d) Ultrasonication
In the context of sterility testing, what does IP stand for?
a) International Pharmacopoeia
b) Indian Pharmacopoeia
c) Internal Procedure
d) Inoculation Protocol
Which type of product is most likely to be tested using the membrane filtration method?
a) Powders
b) Liquids
c) Tablets
d) Ointments
What is the significance of the 14-day incubation period in sterility testing?
a) To allow sufficient time for slow-growing microorganisms to proliferate
b) To shorten the testing process
c) To increase the accuracy of pH measurement
d) To ensure complete chemical reaction
Which medium is typically used for the detection of fungi in sterility testing?
a) Sabouraud Dextrose Medium
b) Fluid Thioglycollate Medium
c) Soybean Casein Digest Medium
d) Nutrient Agar
What is the main objective of sterility testing in pharmaceutical products?
a) To verify the chemical composition of the product
b) To ensure the product is free from viable contaminating microorganisms
c) To measure the product’s viscosity
d) To determine the product’s expiry date
In sterility testing, what is the role of aseptic technique?
a) To promote the growth of microorganisms
b) To prevent contamination of the test samples
c) To speed up the testing process
d) To alter the pH of the medium
Which of the following is a key factor in ensuring the accuracy of sterility tests?
a) Proper sample size
b) Sterility of testing equipment
c) Appropriate incubation conditions
d) All of the above
What does BP stand for in the context of pharmacopeia?
a) Basic Pharmacology
b) British Pharmacopoeia
c) Biological Product
d) Bacteriological Protocol
What is the purpose of using incubators in sterility testing?
a) To accelerate the reaction between chemicals
b) To maintain optimal temperature conditions for microbial growth
c) To preserve the physical state of the product
d) To measure the concentration of microorganisms
What is one of the main challenges in sterility testing of solid products?
a) Ensuring complete dissolution of the product
b) Maintaining constant temperature
c) Measuring the product’s color
d) Avoiding contamination from the environment
Which regulatory guideline specifies the use of Fluid Thioglycollate Medium for sterility testing?
a) IP
b) BP
c) USP
d) All of the above
What is the significance of performing sterility testing on ophthalmic products?
a) To check the pH of the product
b) To ensure the product does not cause eye infections
c) To determine the viscosity of the product
d) To measure the concentration of active ingredients
Which method is NOT typically used for sterility testing of pharmaceutical products?
a) Direct inoculation
b) Membrane filtration
c) Centrifugation
d) HPLC
What is the role of positive controls in sterility testing?
a) To confirm the effectiveness of the disinfectant
b) To ensure the test system can support microbial growth
c) To verify the pH of the medium
d) To check the color of the product
Which of the following is a critical parameter to monitor during the incubation period in sterility testing?
a) pH of the medium
b) Temperature
c) Light intensity
d) Air pressure
What is the primary reason for performing sterility testing on pharmaceutical products?
a) To confirm the absence of viable contaminating microorganisms
b) To measure the chemical properties of the product
c) To assess the physical appearance of the product
d) To determine the product’s shelf life
For more regular updates you can visit our social media accounts,
Instagram: Follow us
Facebook: Follow us
WhatsApp: Join us
Telegram: Join us