Pharmacy Practice MCQ » PHARMACAREERS

Pharmacy Practice MCQ, in this article we will solve, Practice MCQ under subject Microbiology. Read following article for your reference.

Assessment Of New Antibiotics » PHARMACAREERS

What is the primary goal of assessing new antibiotics?
- a) To determine the flavor
- b) To evaluate their efficacy and safety
- c) To reduce production costs
- d) To enhance color
Which phase of clinical trials primarily assesses the safety of a new antibiotic?
- a) Phase I
- b) Phase II
- c) Phase III
- d) Phase IV
What is the purpose of conducting in vitro studies in antibiotic assessment?
- a) To evaluate the cost-effectiveness
- b) To test the antibiotic’s efficacy against specific pathogens
- c) To analyze the flavor
- d) To determine the packaging requirements
What is the significance of MIC (Minimum Inhibitory Concentration) in antibiotic assessment?
- a) It measures the time taken for bacteria to die
- b) It indicates the lowest concentration of an antibiotic that inhibits bacterial growth
- c) It evaluates the toxicity of the antibiotic
- d) It assesses the antibiotic’s stability
Which assay is commonly used to determine the bactericidal activity of an antibiotic?
- a) Disk diffusion assay
- b) Broth dilution test
- c) Time-kill assay
- d) Spectrophotometric assay
What does the term “broad-spectrum antibiotic” refer to?
- a) An antibiotic that targets a specific type of bacteria
- b) An antibiotic effective against a wide range of bacteria
- c) An antibiotic that enhances flavor
- d) An antibiotic used for viral infections
Which regulatory body is responsible for approving new antibiotics in the United States?
- a) WHO
- b) FDA
- c) EMA
- d) NIH
What is the primary focus of Phase III clinical trials in antibiotic assessment?
- a) Evaluating safety
- b) Assessing cost-effectiveness
- c) Testing efficacy and monitoring side effects
- d) Determining packaging requirements
Why are animal studies conducted during the assessment of new antibiotics?
- a) To evaluate the antibiotic’s taste
- b) To test the antibiotic’s efficacy and safety in a living organism
- c) To determine the antibiotic’s color
- d) To analyze the antibiotic’s packaging
Which method is used to assess the pharmacokinetics of a new antibiotic?
- a) Disk diffusion assay
- b) Broth dilution test
- c) Time-kill assay
- d) Blood concentration analysis
What is the purpose of post-marketing surveillance in antibiotic assessment?
- a) To evaluate the antibiotic’s flavor
- b) To monitor the antibiotic’s safety and efficacy in the general population
- c) To determine the antibiotic’s packaging requirements
- d) To assess the antibiotic’s stability
Which term describes the ability of an antibiotic to kill bacteria?
- a) Bacteriostatic
- b) Bactericidal
- c) Antiviral
- d) Antifungal
What is the primary focus of Phase II clinical trials in antibiotic assessment?
- a) Evaluating safety
- b) Testing efficacy
- c) Monitoring side effects
- d) Determining packaging requirements
Which factor is NOT typically evaluated during the assessment of a new antibiotic?
- a) Efficacy
- b) Safety
- c) Flavor
- d) Pharmacokinetics
What is the role of a control group in clinical trials for new antibiotics?
- a) To test the flavor
- b) To provide a baseline for comparing the effects of the antibiotic
- c) To enhance the color
- d) To determine packaging requirements
Which method is used to determine the susceptibility of bacteria to an antibiotic?
- a) Disk diffusion assay
- b) Broth dilution test
- c) Time-kill assay
- d) Spectrophotometric assay
What is the importance of pharmacodynamics in the assessment of new antibiotics?
- a) To evaluate the cost-effectiveness
- b) To study the drug’s effects on the body
- c) To analyze the antibiotic’s flavor
- d) To determine packaging requirements
What is the purpose of conducting resistance testing in antibiotic assessment?
- a) To evaluate the antibiotic’s taste
- b) To determine the potential for bacteria to develop resistance
- c) To assess the antibiotic’s color
- d) To analyze the antibiotic’s packaging
Which assay measures the zone of inhibition to assess antibiotic efficacy?
- a) Disk diffusion assay
- b) Broth dilution test
- c) Time-kill assay
- d) Spectrophotometric assay
What does the term “narrow-spectrum antibiotic” refer to?
- a) An antibiotic effective against a specific type of bacteria
- b) An antibiotic effective against a wide range of bacteria
- c) An antibiotic that enhances flavor
- d) An antibiotic used for viral infections
Which organization provides guidelines for the assessment of new antibiotics?
- a) WHO
- b) FDA
- c) EMA
- d) All of the above
What is the significance of conducting toxicity studies in antibiotic assessment?
- a) To evaluate the antibiotic’s flavor
- b) To determine the safety of the antibiotic
- c) To assess the antibiotic’s color
- d) To analyze the antibiotic’s packaging
Which phase of clinical trials involves large-scale testing of the antibiotic in diverse populations?
- a) Phase I
- b) Phase II
- c) Phase III
- d) Phase IV
What is the purpose of using placebo-controlled trials in antibiotic assessment?
- a) To evaluate the antibiotic’s taste
- b) To determine the antibiotic’s efficacy compared to a placebo
- c) To assess the antibiotic’s color
- d) To analyze the antibiotic’s packaging
Which factor is considered when determining the dosing regimen of a new antibiotic?
- a) The antibiotic’s flavor
- b) The antibiotic’s efficacy and safety
- c) The antibiotic’s packaging
- d) The antibiotic’s color
What is the role of microbiological assays in antibiotic assessment?
- a) To evaluate the cost-effectiveness
- b) To test the antibiotic’s efficacy against specific pathogens
- c) To analyze the antibiotic’s flavor
- d) To determine the packaging requirements
Which term describes the lowest concentration of an antibiotic that prevents visible growth of bacteria?
- a) MIC (Minimum Inhibitory Concentration)
- b) MBC (Minimum Bactericidal Concentration)
- c) LD50 (Lethal Dose 50)
- d) EC50 (Effective Concentration 50)
What is the significance of pharmacokinetic studies in antibiotic assessment?
- a) To evaluate the antibiotic’s flavor
- b) To study how the drug is absorbed, distributed, metabolized, and excreted by the body
- c) To determine the antibiotic’s packaging requirements
- d) To assess the antibiotic’s color
What is the purpose of using animal models in the assessment of new antibiotics?
- a) To evaluate the antibiotic’s taste
- b) To test the antibiotic’s efficacy and safety in a living organism
- c) To determine the antibiotic’s color
- d) To analyze the antibiotic’s packaging
What is the primary focus of Phase IV clinical trials in antibiotic assessment?
- a) Evaluating safety
- b) Testing efficacy
- c) Monitoring long-term effects and post-marketing surveillance
- d) Determining packaging requirements

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