Pharmacy Practice MCQ, in this article we will solve, Practice MCQ under subject physical pharmaceutics II. Read following article for your reference.
- Stabilization of medicinal agents primarily aims to:
- A. Increase bioavailability
- B. Prevent degradation
- C. Enhance solubility
- D. Improve taste
- Common chemical reactions leading to drug degradation include:
- A. Hydrolysis and oxidation
- B. Reduction and polymerization
- C. Sublimation and dissolution
- D. Adsorption and desorption
- Which of the following factors can influence drug stability?
- A. Temperature
- B. Light
- C. pH
- D. All of the above
- Hydrolysis of medicinal agents involves reaction with:
- A. Oxygen
- B. Hydrogen
- C. Water
- D. Light
- Which of the following functional groups is most susceptible to hydrolysis?
- A. Ester
- B. Amine
- C. Alcohol
- D. Ketone
- To prevent hydrolysis, medicinal agents are often formulated with:
- A. Antioxidants
- B. Preservatives
- C. Buffers
- D. Emulsifiers
- Which of the following is a common method to stabilize drugs against hydrolysis?
- A. Reducing moisture exposure
- B. Increasing storage temperature
- C. Enhancing light exposure
- D. Decreasing drug solubility
- The presence of which ion can accelerate hydrolysis?
- A. Sodium
- B. Potassium
- C. Hydrogen
- D. Magnesium
- Hydrolysis reactions are typically faster in:
- A. Solid-state formulations
- B. Aqueous solutions
- C. Non-aqueous solutions
- D. Gas-phase formulations
- Oxidation reactions in medicinal agents typically involve:
- A. Loss of electrons
- B. Gain of electrons
- C. Formation of covalent bonds
- D. Breaking of hydrogen bonds
- Which of the following conditions can accelerate oxidation?
- A. High humidity
- B. High temperature
- C. Presence of metal ions
- D. All of the above
- Antioxidants are added to medicinal formulations to:
- A. Enhance taste
- B. Prevent microbial growth
- C. Inhibit oxidation
- D. Increase solubility
- An example of an antioxidant used in pharmaceuticals is:
- A. Sodium chloride
- B. Ascorbic acid
- C. Calcium carbonate
- D. Magnesium sulfate
- Oxidation reactions are most likely to occur in the presence of:
- A. Oxygen
- B. Nitrogen
- C. Carbon dioxide
- D. Helium
- Stabilization against oxidation can be achieved by:
- A. Adding chelating agents
- B. Decreasing storage temperature
- C. Using amber-colored containers
- D. All of the above
- Reducing the exposure of medicinal agents to light is typically achieved by using:
- A. Transparent containers
- B. Amber-colored containers
- C. Metal containers
- D. Plastic containers
- The addition of buffer solutions to a pharmaceutical formulation aims to:
- A. Change the drug’s color
- B. Maintain a constant pH
- C. Increase the drug’s solubility
- D. Enhance the drug’s taste
- Chelating agents are used in pharmaceutical formulations to:
- A. Bind metal ions
- B. Increase drug solubility
- C. Enhance taste
- D. Act as preservatives
- Which of the following is not a method of stabilizing medicinal agents against degradation?
- A. Using antioxidants
- B. Increasing storage temperature
- C. Reducing exposure to light
- D. Adding chelating agents
- A common chelating agent used in pharmaceuticals is:
- A. EDTA (ethylenediaminetetraacetic acid)
- B. Sodium chloride
- C. Ascorbic acid
- D. Calcium carbonate
- Which type of packaging is preferred to protect pharmaceuticals from oxidation and hydrolysis?
- A. Plastic bottles
- B. Amber glass bottles
- C. Metal cans
- D. Transparent glass bottles
- Refrigeration is used in pharmaceutical storage to:
- A. Improve taste
- B. Reduce degradation rate
- C. Enhance solubility
- D. Increase microbial growth
- To prevent hydrolysis, pharmaceutical products should be stored in:
- A. High humidity environments
- B. Low humidity environments
- C. Light-exposed areas
- D. High temperature areas
- The main purpose of using desiccants in pharmaceutical packaging is to:
- A. Maintain humidity
- B. Absorb moisture
- C. Provide a barrier to light
- D. Enhance drug solubility
- Which material is commonly used for blister packaging of pharmaceuticals to prevent degradation?
- A. Cardboard
- B. Plastic
- C. Aluminum foil
- D. Paper
- What is the primary purpose of adding preservatives to pharmaceutical formulations?
- A. Enhance stability
- B. Improve taste
- C. Prevent microbial growth
- D. Increase solubility
- Which of the following environmental factors is least likely to cause drug degradation?
- A. Low humidity
- B. High temperature
- C. High humidity
- D. Light exposure
- The term “shelf life” refers to:
- A. The time a drug can be stored before use
- B. The time taken to manufacture a drug
- C. The period during which the drug remains effective
- D. The total time from production to consumption
- The stability of a pharmaceutical product can be increased by:
- A. Using appropriate excipients
- B. Storing under recommended conditions
- C. Protecting from environmental factors
- D. All of the above
- Which factor does not significantly affect the chemical stability of pharmaceuticals?
- A. Storage temperature
- B. Dosage form
- C. Relative humidity
- D. Flavoring agents
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