Pharmacy Practice MCQ, in this article we will solve, Practice MCQ on the topic, Principles of Cancer. Read following article for your reference.
Which type of cancer originates in epithelial cells?
A) Sarcoma
B) Carcinoma
C) Leukemia
D) Lymphoma
Which cancer type originates in connective tissues?
A) Carcinoma
B) Leukemia
C) Sarcoma
D) Myeloma
What is the primary site classification of cancer?
A) Based on the tissue type
B) Based on the location of the primary tumor
C) Based on the genetic mutations
D) Based on the patient’s age
Which system is used to classify cancer based on tumor size, lymph node involvement, and metastasis?
A) ABC Classification
B) TNM Classification
C) XYZ Classification
D) PQR Classification
What does the ‘M’ in TNM Classification stand for?
A) Metastasis
B) Mutation
C) Mitosis
D) Myeloma
Which gene mutation is commonly associated with an increased risk of breast and ovarian cancer?
A) TP53
B) BRCA1/BRCA2
C) KRAS
D) EGFR
Which of the following is a known carcinogen?
A) Vitamin C
B) Asbestos
C) Water
D) Oxygen
Which virus is linked to cervical cancer?
A) Hepatitis B
B) Epstein-Barr Virus
C) Human Papillomavirus (HPV)
D) HIV
Which bacteria is associated with an increased risk of stomach cancer?
A) Escherichia coli
B) Helicobacter pylori
C) Streptococcus pneumoniae
D) Staphylococcus aureus
Which lifestyle factor is NOT associated with an increased risk of cancer?
A) Smoking
B) High-fat diet
C) Regular physical activity
D) Excessive alcohol consumption
What is the process of programmed cell death called?
A) Necrosis
B) Apoptosis
C) Angiogenesis
D) Metastasis
Which term describes the formation of new blood vessels to supply a tumor?
A) Apoptosis
B) Angiogenesis
C) Metastasis
D) Proliferation
What is the primary characteristic of cancer cells?
A) Controlled cell growth
B) Uncontrolled cell proliferation
C) Normal cell differentiation
D) Limited lifespan
Which gene type, when mutated, can lead to uncontrolled cell growth?
A) Oncogenes
B) Tumor suppressor genes
C) Housekeeping genes
D) Structural genes
What is the process by which cancer cells spread to other parts of the body?
A) Angiogenesis
B) Apoptosis
C) Metastasis
D) Differentiation
Which component is NOT part of the tumor microenvironment?
A) Immune cells
B) Fibroblasts
C) Extracellular matrix
D) Neurons
Which type of cancer originates in blood-forming tissues?
A) Carcinoma
B) Sarcoma
C) Leukemia
D) Lymphoma
Which factor is NOT a known cause of genetic mutations leading to cancer?
A) UV radiation
B) Tobacco smoke
C) Regular exercise
D) Inherited genetic mutations
Which stage of cancer is characterized by the spread to distant organs?
A) Stage I
B) Stage II
C) Stage III
D) Stage IV
Which virus is associated with liver cancer?
A) Human Papillomavirus (HPV)
B) Hepatitis B and C
C) Epstein-Barr Virus
D) HIV
Which process allows cancer cells to avoid programmed cell death?
A) Angiogenesis
B) Apoptosis
C) Metastasis
D) Evasion of apoptosis
What is the role of tumor suppressor genes?
A) Promote cell growth
B) Inhibit cell growth
C) Repair DNA damage
D) Both B and C
Which type of cancer originates in the lymphatic system?
A) Carcinoma
B) Sarcoma
C) Leukemia
D) Lymphoma
Which lifestyle change can reduce the risk of cancer?
A) Smoking cessation
B) Increased alcohol consumption
C) High-fat diet
D) Sedentary lifestyle
Which term describes the genetic instability seen in cancer cells?
A) Genomic stability
B) Genomic instability
C) Genetic equilibrium
D) Genetic homeostasis
Which cancer type is most commonly associated with asbestos exposure?
A) Lung cancer
B) Skin cancer
C) Breast cancer
D) Prostate cancer
Which factor is NOT typically involved in the pathogenesis of cancer?
A) DNA mutations
B) Uncontrolled cell proliferation
C) Normal cell cycle regulation
D) Angiogenesis
Which of the following is a hallmark of cancer?
A) Controlled cell growth
B) Avoidance of apoptosis
C) Limited replicative potential
D) Normal tissue architecture
Which gene is commonly mutated in many types of cancer and is known as the “guardian of the genome”?
A) BRCA1
B) TP53
C) KRAS
D) EGFR
Which type of cancer is characterized by the presence of abnormal plasma cells in the bone marrow?
A) Carcinoma
B) Sarcoma
C) Leukemia
D) Myeloma
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