Receptor Theories and Classification of Receptors, Regulation of Receptors Receptors are fundamental components in the field of pharmacology, playing a crucial role in mediating the effects of drugs and endogenous substances on the body. Understanding how receptors function, their classification, and the principles that govern their behaviour is essential for developing new therapeutic agents and … Read more
Enzyme Induction, Enzyme Inhibition, Kinetics of Elimination Pharmacology, the science of drugs and their effects on living systems, is a cornerstone of medical and pharmaceutical education. Among the many facets of pharmacology, understanding how drugs are metabolized in the body is crucial for predicting their efficacy and safety. This article delves into three key concepts … Read more
Pharmacodynamics- Principles and Mechanism of Drug Action Pharmacodynamics, a core area of pharmacology, delves into the intricate interactions between drugs and the biological systems they affect. Unlike pharmacokinetics, which focuses on the absorption, distribution, metabolism, and excretion of drugs, pharmacodynamics explores the effects of drugs on the body and how these effects are achieved. This … Read more
Distribution of drugs Distribution in pharmacokinetics refers to the reversible movement of a medication from one part of the body to another. A medication needs to be dispersed into intracellular and interstitial fluids after it is directly administered or absorbed and goes into systemic circulation. Once a medication enters the bloodstream, it is dispersed to … Read more
Absorption of drugs Absorption is defined as the movement of drugs or medications from its site of administration into the bloodstream. The rate of absorption is just as significant as the portion of the administered dose that is absorbed. The medication must pass through biological membranes, unless it is administered intravenously. Absorption is governed by … Read more
Pharmacokinetics Pharmacokinetics is defined as the quantitative study of a drug’s entry, passage through, and exit from the body. The pharmacokinetic properties of the drug determine its concentration at the site of action, which in turn affects the intensity of response. The route of administration, dosage, latency of onset, time of peak action, duration of … Read more